University of Oklahoma Health Sciences Center

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Author/s:

Azadeh Lankarani-Fard, Maria Romanova, Zhaoping Li

Date Added:

July 1, 2025

Journal/Publication:

Journal of General Internal Medicine

Publication Date:

March 31, 2025

Volume:

Pages:

1735–1741

URL:

Reframing Micronutrient Deficiencies for Modern times: A Review

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Article

DOI (1):

10.1007/s11606-025-09481-y

PMID (1):

40164931

Keywords

food insecurity

micronutrient deficiency

vitamin deficiency

MeSH

Micronutrient deficiencies

RPR Commentary

A review of the risk factors for and consequences of micronutrient deficiencies. James W. Mold, MD, MPH

Abstract

Micronutrient deficiencies are often discounted in as an entity of the past when access to quality nutrition was scarce. However modern-day conditions such as hemodialysis, complex medication interactions, parenteral nutrition, gastrointestinal resections, institutional living, and substance use can place patients at risk. The metabolic demands of critical illness during prolonged hospitalization may provide added stressors. Food insecurity with reliance on inexpensive calorie-rich, nutrient poor diet may lead to deficiency without overt evidence of malnutrition. Moreover, clinical presentation may be subtle and easily attributed to other diagnoses. Increased awareness of current risk factors is essential for detection and treatment.

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