Management of Heart Failure in 2019-2020, Part 1
Date Added:
January 3, 2020
Journal/Publication:
JN Learning
Publisher:
JAMA
Publication Date:
September 1, 2016
Type:
Clinical Research Results
Format:
Video
Abstract
Educational Objective
To understand the effects of sacubitril-valsartan vs enalapril on proximal aortic stiffness, cardiac remodeling, and cardiac contractile function among patients with heart failure with reduced ejection fraction (HFrEF).
Text Availability
Commercial full text (fees may apply)
RPR Commentary
This 16 min audiotape reviews the results of recent studies indicating that systolic CHF patients benefit from blocking an additional compensatory pathway, the neprilysin pathway, with the combination agent, sacubitril-valsartin if they remain symptomatic on an ACEI or ARB. James W. Mold, MD, MPH