Duloxetine: Painful Diabetic Neuropathy and Fibromyalgia
Date Added:
October 31, 2018
Journal/Publication:
Bandolier Journal
Publisher:
Bandolier
Type:
Meta-analyses, Reviews, and Guidelines
Abstract
Clinical bottom line
There is good evidence that duloxetine at doses of 60 or 120 mg daily helps some people with painful diabetic neuropathy or fibromyalgia. The NNT for one person to have at least 50% pain relief is about 6. Nausea, somnolence constipation and reduced appetite are common adverse events.
Text Availability
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RPR Commentary
There is good evidence that duloxetine helps some patients with either chronic neuropathic pain or fibromyalgia; 60mg/day worked just as well as 120mg/day.