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Diagnosis of Lyme Disease

Author/s: 
Pitrak, D, Nguyen, C. T., Cifu, A. S.
Date Added: 
March 10, 2022
Journal/Publication: 
Journal of the American Medical Association
Publisher: 
American Medical Association
URL: 
Diagnosis of Lyme Disease
Type: 
Meta-analyses, Reviews, and Guidelines
Format: 
Article
DOI (1): 
10.1001/jama.2022.0081
Keywords 
Lyme disease
diagnosis
US
tick-borne illness
MeSH 
incidence
Myocarditis
Tick Bites
Lyme Disease
Ticks

RPR Commentary

While there have been very few documented cases of Lyme disease in Oklahoma, diagnostic testing is often considered. This is a concise summary of the evidence regarding diagnostic tests for Lyme disease and how and when to use or not use them. James W. Mold, MD, MPH

Abstract

Lyme disease is the most common tick-borne illness in the US, occurring predominantly in the Northeast, the upper Midwest, and Northern California, with increasing incidence and geographic range.1 Lyme disease can cause a skin lesion at the site of the initial tick bite as well as disseminated disease, including neuropathy, meningitis, acute myocarditis/pericarditis (often with associated conduction abnormalities), and arthritis. Accurate diagnosis is the first step in the optimal management of Lyme disease.

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