Diagnosis and Management of Hereditary Hemochromatosis
Date Added: 
    November 12, 2022
      Journal/Publication: 
    JAMA
      Publisher: 
    Massachusetts Medical Society
      Publication Date: 
    November 8, 2022
      Issue: 
    18
      Volume: 
    328
      Pages: 
    1862-1863
      Type: 
    Meta-analyses, Reviews, and Guidelines
      Format: 
    Article
      DOI (1): 
    10.1001/jama.2022.17727
      PMID (1): 
    36346422
      Abstract
Hereditary hemochromatosis (HH) is a heterogeneous genetic disorder that results in unregulated and excessive intestinal iron absorption leading to overabundance of iron deposition in tissue. HH is most common in people of northern European ancestry, for whom the prevalence is 1 case per 300 people.1-3
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RPR Commentary
A updated summary of the pathophysiology, diagnosis, and treatment of hemochromatosis. James W. Mold, MD, MPH