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Perinatal Depression: A Guide to Detection and Management in Primary Care

Author/s: 
Manish H Dama, Ryan J Van Lieshout

Introduction: Existing guidelines for primary care clinicians (PCCs) on the detection and management of perinatal depression (PD) contain important gaps. This review aims to provide PCCs with a summary of clinically relevant evidence in the field.

Methods: A narrative literature review was conducted by searching PubMed and PsycINFO for articles published between 2010 to 2023. Guidelines, systematic reviews, clinical trials, and/or observational studies were all examined.

Results: Screening with the Edinburgh Postnatal Depression Scale or Patient Health Questionnaire-9 followed by a diagnostic evaluation for major depressive disorder in probable cases can enhance PD detection. At-risk individuals and mild to moderate PD should be referred for cognitive behavioral therapy or interpersonal psychotherapy when available. Selective serotonin reuptake inhibitors should be used for moderate to severe PD, with sertraline, escitalopram, or citalopram being preferred first. Using paroxetine or clomipramine in pregnancy, and fluoxetine or doxepin during lactation is generally not preferred. Gestational antidepressant use is associated with a small increase in risk of reduced gestational age at birth, low birth weight, and lower APGAR scores, though whether these links are causal is unclear. Sertraline and paroxetine have the lowest rate of adverse events during lactation. Consequences of untreated PD can include maternal and offspring mortality, perinatal complications, poor maternal-infant attachment, child morbidity and maltreatment, less breastfeeding, and offspring developmental problems.

Conclusions: These clinically relevant data can support the delivery of high-quality care by PCCs. Risks and benefits of PD treatments and the consequences of untreated PD should be discussed with patients to support informed decision making.

Keywords 
breast feeding Interpersonal Psychotherapy Lactation Postpartum Postpartum Depression Pregnancy Psychiatry Psychosocial Intervention selective serotonin reuptake inhibitors Surveys and Questionnaires

Adenotonsillectomy for Snoring and Mild Sleep Apnea in Children

Author/s: 
Susan Redline, Kaitlyn Cook, Ronald D. Chervin

Question: Among children who snore without frequent obstructive events, does early adenotonsillectomy compared with watchful waiting with supportive care improve neurodevelopment, behavior, or other symptoms at 12-month follow-up?

Findings: In this randomized clinical trial of 458 children with mild sleep-disordered breathing (SDB), adenotonsillectomy compared with watchful waiting resulted in no significant differences in executive function or attention at 12 months. The adenotonsillectomy group had improved quality of life, symptoms, behavior, and blood pressure, which were among the secondary outcomes measured.

Meaning: In children with mild SDB, adenotonsillectomy resulted in no statistically significant differences in changes in executive function or attention but led to improved secondary outcomes including symptoms, behavior, and blood pressure.

Keywords 
children sleep apnea snoring surgery

What Parents Should Know About Gun Safety in the Home and Vehicle

Author/s: 
Rebecca J. Palmer, Leila H. DeWitt, Lindsay A. Thompson

This Patient Page describes safety measures parents can take to protect children from gun violence.

Guns are now the leading cause of death for children in the US.

Guns are even more lethal than motor vehicle crashes. The reasons for this gun violence increase in children are multiple, including a rapid rise in gun purchases, an increase in depression and anxiety in children and adolescents, and widespread stress from a global pandemic. The causes of these injuries and deaths vary by age. Younger children are more commonly injured unintentionally. Curious toddlers can find guns and fire them quickly. Older children and adolescents are more likely to be harmed by homicide or suicide.

The most important factor for children being injured or killed by guns is having a gun in the home where a child lives or the car where a child rides. Adults must make sure their guns are stored safely to prevent access by a child or adolescent. There are gun locks, safes, and other techniques to promote safer storage. As an additional safety measure, caregivers should strongly consider removing guns entirely from the home or vehicle, especially when children are older than about 11 years. These youths know how to find and access guns, even if they are stored safely. Considering the increase in mood disorders and risk of suicidal behaviors in older children and adolescents, they should not be around guns.

Parents and caregivers should follow the Be SMART framework to improve gun safety:

S: Secure all guns in your home and vehicle.

M: Model responsible behavior around guns.

A: Ask about unsecured guns in other homes.

R: Recognize the role of guns in suicide.

T: Tell others to Be SMART.

Keywords 
gun ownership gun safety children children's health Firearms pediatrics

What Is Lead Poisoning?

Author/s: 
Walter, Walter, Kristin

Lead poisoning usually causes no immediate symptoms, but over time, lead causes damage to developing brains, so children exposed to lead (even at low levels) can have slowed growth and development and problems with learning, behavior, hearing, and speech that may be permanent. Adults with lead poisoning are at increased risk of high blood pressure, heart disease, decline in cognitive function, anxiety, depression, and death.

Keywords 
fetus breast feeding lead levels

Foreign body aspiration in children

Author/s: 
Hutchinson, K. A., Turkdogan, S., Nguyen, L. H. P.

In Canada, choking or suffocation accounts for about 40% of unintentional deaths among children younger than 1 year.
Round and cylindrical food or other foreign bodies (e.g., hot dogs, sausages, grapes, marbles) pose the greatest risk. Uninflated balloons are hazardous owing to their ability to form a complete seal of the airway.

Keywords 
bronchoscopy aspiration choking children foreign body aspiration

Foreign body aspiration in children

Author/s: 
Hutchinson, K. A., Turkdogan, S., Nguyen, L. H. P.

In Canada, choking or suffocation accounts for about 40% of unintentional deaths among children younger than 1 year.
Round and cylindrical food or other foreign bodies (e.g., hot dogs, sausages, grapes, marbles) pose the greatest risk. Uninflated balloons are hazardous owing to their ability to form a complete seal of the airway.

Keywords 
bronchoscopy aspiration choking children foreign body aspiration

Air Quality Index and Childhood Asthma: A Pilot Randomized Clinical Trial Intervention

Author/s: 
Rosser, F. J., Rothenberger, S. D., Han, Y., Forno, E., Celedón, J. C.

Introduction: To reduce air pollution exposure, the U.S. asthma guidelines recommend that children check the Air Quality Index before outdoor activity. Whether adding the Air Quality Index and recommendations to asthma action plans reduces exacerbations and improves control and quality of life in children with asthma is unknown.

Methods: A pilot, unblinded, randomized clinical trial of 40 children with persistent asthma, stratified by age and randomized 1:1, recruited from the University of Pittsburgh Medical Center Children's Hospital of Pittsburgh (Pittsburgh, PA) was conducted. All participants received asthma action plans and Air Quality Index education. The intervention group received printed Air Quality Index information and showed the ability to use AirNow. Asthma exacerbations were assessed through a questionnaire, asthma control was assessed with the Asthma Control Test and Childhood Asthma Control Test, and quality of life was assessed with the Pediatric Asthma Quality of Life Questionnaire. After randomization (July-October 2020), participants were followed monthly for 6 months (exit January-March 2021). Outcome differences between groups were evaluated at the exit visit and over time (analysis was in 2021).

Results: At randomization, there were no significant differences in age, sex, race, or asthma severity. At exit, more intervention participants checked the Air Quality Index (63% vs 15%) with no differences in the proportion of asthma exacerbations or mean Childhood Asthma Control Test or Pediatric Asthma Quality of Life Questionnaire scores. The mean change in Asthma Control Test score was higher in the intervention group (change in Asthma Control Test=2.00 vs 0.15 for the control), which was modified by time (β=1.85, CI=0.09, 3.61). Physical activity was decreased overall and showed modification by treatment and time.

Conclusions: Addition of the Air Quality Index to asthma action plans led to improved asthma control by Asthma Control Test scores but may decrease outdoor activity.

Keywords 
children quality of life asthma air pollution United States

A Review on Lumps, Bumps, and Birthmarks: When and Why to Refer

Author/s: 
Brown, K. W., Lucas, E., Hoppe, I. C., Humphries, L. S.

Skin lesions of the face, trunk, and extremities are commonly seen in the pediatric population. Although most of these lesions are benign, they can be locally destructive or interfere with normal development. Recognition and diagnosis of these lesions allow for timely workup and referral; treatment, if needed; and facilitation of parental discussions. The purpose of this article is to review common pediatric skin and soft-tissue lesions-or "lumps, bumps, and birthmarks"-to assist with diagnosis, workup, and guidelines for referral to pediatric plastic surgery. [Pediatr Ann. 2023;52(1):e23-e30.].

Keywords 
skin diseases pediatric diagnosis birthmarks assessment
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