Importance: Obesity affects approximately 21% of US adolescents and is associated with insulin resistance, hypertension, dyslipidemia, sleep disorders, depression, and musculoskeletal problems. Obesity during adolescence has also been associated with an increased risk of mortality from...
Recent Resources
Chronic urticaria: unmet needs, emerging drugs, and new perspectives on personalised treatment
Chronic urticaria is a common and debilitating mast cell-driven skin disease presenting with itchy wheals, angio-oedema, or both. Chronic urticaria is classified as spontaneous (without definite triggers) and inducible (with definite and subtype-specific triggers; eg, cold or pressure). Current...
Heat-Related Illness in Athletes
This JAMA Insights discusses heat-related illness in athletes, including risk factors, prevention, symptoms, and management.
Medications for Obesity: A Review
Importance: Obesity affects approximately 19% of women and 14% of men worldwide and is associated with increased morbidity. Antiobesity medications (AOMs) modify biological processes that affect appetite and significantly improve outcomes, such as type 2 diabetes, hypertension, and dyslipidemia...
Interventions for High Body Mass Index in Children and Adolescents: US Preventive Services Task Force Recommendation Statement
Importance: Approximately 19.7% of children and adolescents aged 2 to 19 years in the US have a body mass index (BMI) at or above the 95th percentile for age and sex, based on Centers for Disease Control and Prevention growth charts from 2000. The prevalence of high BMI increases with age and is...
Acute Abdomen in the Modern Era
Acute abdominal pain is one of the most common symptoms in patients presenting to the emergency department and accounts for 5 to 10% of all emergency department visits. Pathophysiological conditions that lead to surgical interventions in such patients are mainly gastrointestinal obstruction,...
Diagnosis and Management of Celiac Disease
Guideline title American College of Gastroenterology Guidelines Update: Diagnosis and Management of Celiac Disease
Release date January 2023
Prior version May 2013
Developer and funding source American College of Gastroenterology
Target population Children and adults...
Revisiting Race and the Benefit of RAS Blockade in Heart Failure: A Meta-Analysis of Randomized Clinical Trials
Importance: Concerns have arisen that renin-angiotensin system (RAS) blockers are less effective in Black patients than non-Black patients with heart failure and reduced ejection fraction (HFrEF).
Objective: To determine whether the effects of RAS blockers on cardiovascular outcomes...
Perioperative Management of Antithrombotic Therapy
Guideline title Perioperative Management of Antithrombotic Therapy: An American College of Chest Physicians Clinical Practice Guideline
Release date November 2022
Developer and funding source American College of Chest Physicians
Target population Patients taking oral...
Interventions for High Body Mass Index in Children and Adolescents: US Preventive Services Task Force Recommendation Statement
Importance: Approximately 19.7% of children and adolescents aged 2 to 19 years in the US have a body mass index (BMI) at or above the 95th percentile for age and sex, based on Centers for Disease Control and Prevention growth charts from 2000. The prevalence of high BMI increases with age and is...