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Recent Resources

Neutropenia

Author/s: Mithoowani, Siraj, Cameron, L., Crowther, M. A.

»Neutropenia is seen in 5%–10% of healthy people
Based on absolute neutrophil count, neutropenia is commonly defined as
mild (1.0–1.5 × 109
/L), moderate (0.5–0.9 × 109
/L) or severe (< 0.5 × 109
/L).1
However, the reference interval is specific to the...

Keywords/Tags:
neutropenia complete blood count neutrophil count treatment Autoimmune Diseases

Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2022 Recommendations of the International Antiviral Society-USA Panel

Author/s: Gandhi, R. T., Bedimo, R., Hoy, J. F.

Importance: Recent advances in treatment and prevention of HIV warrant updated recommendations to guide optimal practice.

Objective: Based on a critical evaluation of new data, to provide clinicians with recommendations on use of antiretroviral drugs for the treatment and prevention of...

Keywords/Tags:
Antiviral Agents Pharmaceutical Preparations Anti-Retroviral Agents HIV Anti-HIV Agents

The American Society of Pain and Neuroscience (ASPN) Evidence-Based Clinical Guideline of Interventional Treatments for Low Back Pain

Author/s: Sayed, D., Grider, J., Strand, N., Hagedorn, J. M., Falowski, S., Lam, C. M., Francio, V. T., Beall, D. P., Tomycz, N. D., Davanzo, J. R., Aiyer, R., Lee, D. W., Kaila, H., Sheen, S., Malinowski, M. N., Verdolin, M., Vodapally, S., Carayannopoulos, A., Jain, S., Azeem, N., Tolba, R., Chien, G. C. C., Ghosh, P., Mazzola, A. J., Amirdelfan, K., Chakravarthy, K., Petersen, E., Schatman, M. E., Deer, T.

Introduction
Painful lumbar spinal disorders represent a leading cause of disability in the US and worldwide. Interventional treatments for lumbar disorders are an effective treatment for the pain and disability from low back pain. Although many established and emerging interventional...

Keywords/Tags:
evidence-based interventional treatments Low Back Pain lumbar spinal disorders Pain

Practical Management of Lumps and Bumps of the Fingers, Hand, and Wrist

Author/s: Ho Gung, J., Mehrzad, R., Bhatt, R. A.

Background: Primary care physicians encounter many patients who present with lumps and bumps on their fingers, hands, and wrists. Some benign lesions including ganglion cysts, epidermal inclusion cysts, and giant cell tumors of the tendon sheath that are benign and can be managed by primary care...

Keywords/Tags:
Dupuytren’s Contracture Epidermal Inclusion Cysts Fingers, Ganglion Cysts Giant Cell Tumors plastic surgery primary health care

Management of chronic respiratory diseases during viral pandemics: A concise review of guidance and recommendations

Author/s: Sharma, P., Mishra, M., Dua, R., Saini, L. K., Sindhwani, G.

Coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an acute respiratory disease that can lead to respiratory failure and death. Although anticipated that patients with chronic respiratory diseases would be at increased risk...

Keywords/Tags:
asthma interstitial lung disease management recommendations copd COVID-19

Review of systemic and syndromic complications of cannabis use: A review

Author/s: Shah, J., Fermo, O.

Purpose of review: Prescribed and non-prescribed cannabis use is common. Providers in specialties treating chronic pain – primary care, pain management, and neurology–will be coming across medical cannabis as a treatment for chronic pain, regardless of whether they are prescribers. It is...

Keywords/Tags:
neurology marijuana Pain managing pain complications of cannabis use

Prescribing for common complications of spinal cord injury

Author/s: McColl, M. A., Gupta, S., McColl, A., Smith, K.

Objective: To describe prescribing patterns for 3 common complications associated with spinal cord injury (SCI) and to provide family doctors with strategies for optimizing the care of patients with SCI.

Sources of information: Results of a nationwide survey of prescription medication use...

Keywords/Tags:
Pain therapy Muscle spasticity spinal cord injuries common complications prescriptions

Long-Term Health Outcomes in Obstructive Sleep Apnea: A Systematic Review of Comparative Studies Evaluating Positive Airway Pressure and the Validity of Breathing Measures as Surrogate Outcomes

Author/s: Balk, E. M., Adam, G. P., Cao, W., Bhuma, M. R., Forbes, S., Mehta, S., Panagiotou, O., D'Ambrosio, C., Trikalinos, T. A.

Background. Obstructive sleep apnea (OSA) is a disorder characterized by periods of airflow
cessation (apnea) or reduced airflow (hypopnea) during sleep. The diagnosis and severity of
OSA, and response to therapy, have historically been assessed using the apnea-hypopnea index
(...

Keywords/Tags:
CPAP Obstructive sleep apnea sleep apnea systematic review breathing measures

Health benefits of physical activity: the evidence

Author/s: Warburton, D. E. R., Nicol, C. W., Bredin, S. S. D.

The primary purpose of this narrative review was to evaluate the current literature and to provide further insight into the role physical inactivity plays in the development of chronic disease and premature death. We confirm that there is irrefutable evidence of the effectiveness of regular...

Keywords/Tags:
Health Behavior exercise Health Status Chronic Disease physical activity

Individualized antidepressant therapy in patients with major depressive disorder: Novel evidence-informed decision support tool

Author/s: Chin, T., Huyghebaert, T., Svrcek, C., Oluboka, O.

Objective: To introduce a visual clinical decision support tool to assist with individualizing first-line antidepressant pharmacotherapy for adults with major depressive disorder (MDD) in a Canadian context.

Sources of information: A literature review was conducted with Google Scholar,...

Keywords/Tags:
Systematic Reviews as Topic antidepressive agents Serotonin Uptake Inhibitors Major Depressive Disorder SSRI

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