Interview with John B. Wong, MD, USPSTF member and coauthor of Preexposure Prophylaxis to Prevent Acquisition of HIV: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.
Recent Resources
Stress urinary incontinence and synthetic mesh midurethral slings in women
Stress urinary incontinence has a prevalence of 10%–40% and is considered severe in 3%–17% of women worldwide.1 Diagnosis involves demonstrating involuntary urine leakage with increases in intra-abdominal pressure (e.g., exercising, coughing). On history, it is important to differentiate this...
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Approach to sialadenitis
Objective To provide family physicians with a practical evidence-based approach to the management of patients with sialadenitis.
Sources of information MEDLINE and PubMed databases were searched for English-language research on sialadenitis and other salivary gland disorders, as well as...
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Comparative Efficacy of Pharmacological Treatments for Acne Vulgaris: A Network Meta-Analysis of 221 Randomized Controlled Trials
PURPOSE Acne is an extremely common skin disease with an estimated global prevalence of 9.4%. We aim to provide comprehensive comparisons of the common pharmacological treatments for acne.
METHODS Randomized controlled trials comparing the efficacy of pharmacological therapies for acne...
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Pelvic organ prolapse
Prolapse is found in 41%–50% of adult females, with symptoms of pelvic pressure and vaginal bulge sensation reported by 3%–6% of adult females. Prolapse is diagnosed and staged with physical examination based on the maximum descent of vaginal tissue (anterior, posterior or apex) on Valsalva...
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Clin-STAR corner: 2021 update in musculoskeletal pain in older adults with a focus on osteoarthritis-related pain
Chronic musculoskeletal (MSK) pain remains a leading cause of disability and functional impairment among older adults and is associated with substantial societal and personal costs. Chronic pain is particularly challenging to manage in older adults because of multimorbidity, concerns about...
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Folic Acid Supplementation to Prevent Neural Tube Defects: Preventive Medication
Recommendations made by the USPSTF are independent of the U.S. government. They should not be construed as an official position of the Agency for Healthcare Research and Quality or the U.S. Department of Health and Human Services.
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Low-Dose Aspirin and the Risk of Stroke and Intracerebral Bleeding in Healthy Older People
Importance Low-dose aspirin has been widely used for primary and secondary prevention of stroke. The balance between potential reduction of ischemic stroke events and increased intracranial bleeding has not been established in older individuals.
Objective To establish the risks of...
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Management of Latent Tuberculosis Infection
In theUS, approximately 13million people have latent tuberculosis infection (LTBI),definedaspeoplewhoareinfectedwithMycobacterium
tuberculosiswho do not have symptoms and do not transmit the disease.Without treatment, approximately 5% to 10% of immunocompetent personswithLTBI develop...
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Demystifying breast cancer
The first question a patient often asks their FP after receiving a diagnosis of breast cancer (BC) is “What will my treatment be?” This article will help FPs answer this complex question by reviewing multimodal therapy for BC, which is contingent on molecular subtype and stage.
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