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Recent Resources

Attention Deficit Hyperactivity Disorder: Diagnosis and Treatment in Children and Adolescents Comparative Effectiveness Review No. 203

Author/s: Kemper, AR, Maslow, GR, Hill, S, Namdari, B, Allen LaPoint, NM, Goode, AP, Coeytaux, RR, Befus, D, Kosinski, AS, Bowen, SE, McBroom, AJ, Lallinger, KR, Sanders, GD

Objectives. Attention deficit hyperactivity disorder (ADHD) is a common pediatric neurobehavioral disorder often treated in the primary care setting. This systematic review updates and extends two previous Agency for Healthcare Research and Quality (AHRQ) systematic evidence...

Keywords/Tags:
ADHD attention deficit disorder with hyperactivity ADHD treatment children adolescent

Update: Characteristics of Patients in a National Outbreak of E-cigarette, or Vaping, Product Use–Associated Lung Injuries — United States, October 2019

Author/s: Moritz, E.D., Zapata, L.B., Lekiachvili, A, Glidden, E, Annor, F.B., Werner, A., Ussery, E, Hughes, M.M., Kimball, A, DeSisto, C.L., Kenemer, E.H., Shamout, M, Garcia, M.C., Reagan-Steiner, S, Petersen, E.E., Koumans, E.H., Ritchey, M.D., King, BA, Jones, CM, Briss, PA, Delaney, L, Patel, A, Polen, KD, Sives, K, Meaney-Delman, D, Chatham-Stephens, K, Lung Injury Response Epidemiology/Surveillance Group

What is already known about this topic?

CDC and partners are investigating the ongoing outbreak of e-cigarette, or vaping, product use–associated lung injury (EVALI) in the United States, the District of Columbia, and one U.S. territory.

What is added by...

Keywords/Tags:
vaping lung injury e-cigarettes EVALI e-cigarette or vaping product use-associated lung injury

Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial

Author/s: Hermida, R.C., Crespo, J.J., Domínguez-Sardiña, M, Otero, A., Moyá, A., Ríos, M.T., Sineiro, E., Castiñeira, M.C., Callejas, P.A., Pousa, L., Salgado, J.L., Durán, C., Sánchez, J.J., Fernández, J.R., Mojón, A., Ayala, D.E., Hygia Project Investigators

AIMS:

The Hygia Chronotherapy Trial, conducted within the clinical primary care setting, was designed to test whether bedtime in comparison to usual upon awakening hypertension therapy exerts better cardiovascular disease (CVD) risk reduction.

METHODS AND RESULTS:

In this...

Keywords/Tags:
antihypertensives blood pressure hypertension medication

Association of Treatment With 5α-Reductase Inhibitors and Prostate Cancer Mortality Among Older Adults

Author/s: Kumar, A, Nalawade, V, Riviere, P, Sarkar, RR, Parsons, JK, Murphy, JD, Rose, BS

5α-reductase inhibitors (5-ARIs) are used to treat benign prostatic enlargement, a common condition causing urinary outflow obstruction. They also reduce prostate-specific antigen (PSA) by approximately 50%. Our group has recently published that among US military veterans, 5-ARIs are associated...

Keywords/Tags:
prostate cancer 5-alpha-reductase inhibitors 5α-Reductase Inhibitors 5-ARIs prostate-specific antigen PSA

Bisphosphonates for Postmenopausal Osteoporosis

Author/s: Ensrud, KE, Crandall, CJ

Bisphosphonates are the first-line pharmacologic treatment for postmenopausal osteoporosis and the most commonly prescribed medication for this condition.1 Bisphosphonates, classified as antiresorptive agents,...

Keywords/Tags:
post-menopausal osteoporosis bisphosphonates antiresorptive agents

Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD: A Systematic Review

Author/s: Dobler, CC, Morrow, AS, Farah, MH, Beuschel, B, Majzoub, AM, Wilson, ME, Hasan, B, Seisa, MO, Daraz, L, Prokop, LJ, Murad, MH, Wang, Z

Objectives. To synthesize existing knowledge about the effectiveness and harms of pharmacologic and nonpharmacologic treatments for exacerbations of chronic obstructive pulmonary disease (ECOPD).

Data sources. Embase®, Epub Ahead of Print, In-Process...

Keywords/Tags:
copd chronic obstructive pulmonary disease therapy randomized control trial systematic review

Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial

Author/s: Ordi-Ros, J, Sáez-Comet, L., Pérez-Conesa, M., Vidal, X., Riera-Mestre, A., Castro-Salomó, A., Cuquet-Pedragosa, J., Ortiz-Santamaria, V., Mauri-Plana, M., Solé, C., Cortés-Hernández, J.

BACKGROUND:

The potential role of new oral anticoagulants in antiphospholipid antibody syndrome (APS) remains uncertain.

OBJECTIVE:

To determine whether rivaroxaban is noninferior to dose-adjusted vitamin K antagonists (VKAs) for thrombotic APS.

DESIGN:

3-year...

Keywords/Tags:
rivaroxaban thrombosis wafarin

Primary Prevention of Cardiovascular Disease

Author/s: Jain, A, Davis, AM

Atherosclerotic CVD remains the leading cause of death for people of most racial/ethnic groups. In 2010, the AHA suggested metrics of ideal cardiovascular health in 7 domains (blood pressure, physical activity, cholesterol, diet, weight, smoking, and blood glucose). There have since been...

Keywords/Tags:
CAD coronary artery disease guidelines American Heart Association American College of Cardiology CVD cardiovascular disease primary prevention

Subconcussive Football Hits May Leave a Telltale Signature of Brain Damage

Author/s: Sancar, F

College football players in the United States endure over 1000 head hits every season. Although many don’t produce symptoms such as dizziness or blurred vision that often accompany frank concussion, these “clinically silent” hits are associated with the same type of brain damage as concussion,...

Keywords/Tags:
head injury football brain injury athletes TBI CTE

Unprocessed Red Meat and Processed Meat Consumption: Dietary Guideline Recommendations From the Nutritional Recommendations (NutriRECS) Consortium

Author/s: Johnston, BC, Zeraatkar, D, Han, MA, Vernooij RWM, Valli, C, El Dib, R, Marshall, C, Stover, PJ, Fairweather-Taitt, S, Wojcik, G, Bhatia, F, de Souza, R, Brotons, C, Meerpohl, JJ, Patel, CJ, Djulbegovic, B, Alonso-Coello, P, Bala, MM, Guyatt, GH

DESCRIPTION:

Dietary guideline recommendations require consideration of the certainty in the evidence, the magnitude of potential benefits and harms, and explicit consideration of people's values and preferences. A set of recommendations on red meat and processed meat consumption was...

Keywords/Tags:
meat red meat dietary guideline diet nutrition

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