Author/s: Rebecca Voelker
Bipolar disorder is characterized by mood swings ranging from depressive lows to manic highs.
Bipolar disorder affects about 8 million people in the US and an estimated 40 million individuals worldwide. Symptoms of bipolar disorder typically start between age 15 to 25 years, often with an...
Author/s: Edward G A Iglesia, Mildred Kwan, Yamini V Virkud, Onyinye I Iweala
Importance: An estimated 7.6% of children and 10.8% of adults have IgE-mediated food-protein allergies in the US. IgE-mediated food allergies may cause anaphylaxis and death. A delayed, IgE-mediated allergic response to the food-carbohydrate galactose-α-1,3-galactose (alpha-gal) in mammalian...
Author/s: Kevin Liang, Philip Hui, Samantha Green
Postinfectious cough affects 11%–25% of adults after a respiratory infection
Postinfectious cough is defined as a subacute cough, with symptoms lasting between 3 and 8 weeks.1 The preceding infection triggers an inflammatory cascade, increasing bronchial sensitivity and mucus production,...
Author/s: Jenny Ruiz, Colleen Mathews, Erika Friehling
Childhood leukemia is the most common type of cancer that affects children. Leukemia is a cancer of white blood cells that starts in bone marrow (the soft center part of bones), which produces blood cells. Once a leukemic cell develops, it multiplies quickly in the bone marrow and can prevent...
Author/s: Laura Boucai, Mark Zafereo, Maria E Cabanillas
Importance: Approximately 43 720 new cases of thyroid carcinoma are expected to be diagnosed in 2023 in the US. Five-year relative survival is approximately 98.5%. This review summarizes current evidence regarding pathophysiology, diagnosis, and management of early-stage and advanced thyroid...
Author/s: Mohit Sodhi, Ramin Rezaeianzadeh, Abbas Kezouh, Mahyar Etminan
This database study examines the association between glucagon-like peptide 1 agonists (eg, semaglutide, liraglutide) used for weight loss and reports of gastrointestinal adverse events.
Author/s: Rebecca Voelker
This JAMA Patient Page describes the condition of ulcerative colitis and its symptoms, diagnosis, and treatment options.
Author/s: Ebernella Shirin Dason, Olexandra Koshkina, Crystal Chan, Mara Sobel
KEY POINTS
Polycystic ovarian syndrome (PCOS) is a chronic disorder associated with infertility; miscarriage; adverse pregnancy outcomes; and cardiovascular, metabolic, psychological and neoplastic risks.
DIagnosis of PCOS can be made based on the presence of any 2 of menstrual...
Author/s: Helen James, Warren Harris Lewin
Advance care planning (ACP) was identified as a priority in the 2006 final report of the Public Information and Awareness Working Group of the Canadian Strategy on Palliative and End-of-Life Care.1 An important component of ACP is patients’ understanding of their prognoses, which might include...
Author/s: Mark H Ebell, Henry C Barry, Kanishka Baduni, Gabrielle Grasso
Purpose: We conducted a meta-analysis to evaluate clinically meaningful benefits and harms of monoclonal antibodies targeting amyloid in patients with Alzheimer dementia.
Methods: We searched PubMed, Cochrane CENTRAL, and 5 trial registries, as well as the reference lists of identified...