IMPORTANCE:
The role for aspirin in cardiovascular primary prevention remains controversial, with potential benefits limited by an increased bleeding risk.
OBJECTIVE:
To assess the association of aspirin use for primary prevention with cardiovascular events and bleeding....
The user guide for the Research-to-Practice-Research (RPR) Exchange.
Access to care is a challenge for many of our patients. The College of Family Physicians of Canada (CFPC) and the Royal College of Physicians and Surgeons of Canada (Royal College) recognize that every possible measure must be taken to help ensure access to timely and quality medical and other...
BACKGROUND:
The consequences of influenza in adults are mainly time off work. Vaccination of pregnant women is recommended internationally. This is an update of a review published in 2014. Future updates of this review will be made only when new trials or vaccines become available....
Porphyromonas gingivalis, the keystone pathogen in chronic periodontitis, was identified in the brain of Alzheimer’s disease patients. Toxic proteases from the bacterium called gingipains were also identified in the brain of Alzheimer’s patients, and levels correlated with tau and...
An update for clinicians on the role of low-dose aspirin for prevention of cardiiovascular events from the Healthy Hearts for OK project.
An update for clinicians on the role of blood pressure for prevention of cardiiovascular events from the Healthy Hearts for OK project.
An update for clinicians on the use of statins to prevent cardiiovascular events from the Healthy Hearts for OK project.
An update for clinicians on the importance of smoking cessation for the prevention of cardiiovascular events from the Healthy Hearts for OK project.
BACKGROUND:
Randomised controlled trials (RCTs) of vitamin D to prevent COPDexacerbations have yielded conflicting results.Individual participant data meta-analysis could identify factors that explain this variation.
METHODS:
PubMed, Embase, the Cochrane Central Register of ...
