Primary aldosteronism (PA) is common among patients with hypokalemia and hypertension. Patients with PA are at an increased risk of chronic disease if undiagnosed or untreated. Expert consensus recommends screening for PA in high-risk populations. Most antihypertensive medications can be...
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My Sickle Cell Pain Action Plan
An action plan for patients with sickle cell disease developed by the Uniformed Services University. James W. Mold, MD, MPH
Timing of Allergenic Food Introduction and Risk of Immunoglobulin E-Mediated Food Allergy: A Systematic Review and Meta-analysis
Importance: Earlier egg and peanut introduction probably reduces risk of egg and peanut allergy, respectively, but it is uncertain whether food allergy as a whole can be prevented using earlier allergenic food introduction.
Objective: To investigate associations between timing of...
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What Is Lead Poisoning?
Lead poisoning usually causes no immediate symptoms, but over time, lead causes damage to developing brains, so children exposed to lead (even at low levels) can have slowed growth and development and problems with learning, behavior, hearing, and speech that may be permanent. Adults with lead...
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What Should I Know About Stopping Routine Cancer Screening?
Cancer screening tests are not perfect. Test results may suggest cancer when there is none (false-positive screen). They can also miss cancer even if it is present (false-negative screen). False-positive results can lead to emotional stress and more testing without improving health. Screening...
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Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer
Background
Between 1999 and 2009 in the United Kingdom, 82,429 men between 50 and 69 years of age received a prostate-specific antigen (PSA) test. Localized prostate cancer was diagnosed in 2664 men. Of these men, 1643 were enrolled in a trial to evaluate the effectiveness of treatments,...
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Heart Failure With Preserved Ejection Fraction
Importance Heart failure with preserved ejection fraction (HFpEF), defined as HF with an EF of 50% or higher at diagnosis, affects approximately 3 million people in the US and up to 32 million people worldwide. Patients with HFpEF are hospitalized approximately 1.4 times per year and have an...
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Foreign body aspiration in children
In Canada, choking or suffocation accounts for about 40% of unintentional deaths among children younger than 1 year.
Round and cylindrical food or other foreign bodies (e.g., hot dogs, sausages, grapes, marbles) pose the greatest risk. Uninflated balloons are hazardous owing to their...
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Foreign body aspiration in children
In Canada, choking or suffocation accounts for about 40% of unintentional deaths among children younger than 1 year.
Round and cylindrical food or other foreign bodies (e.g., hot dogs, sausages, grapes, marbles) pose the greatest risk. Uninflated balloons are hazardous owing to their...
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Dynamics of Naturally-Acquired Immunity Against SARS-CoV-2 in Children and Adolescents
Background
To evaluate the duration of protection against reinfection conferred by a previous SARS-CoV-2 infection in children and adolescents.
Methods
We applied two complementary approaches: a matched test-negative, case-control design and a retrospective cohort design. 458,...
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