Bisphosphonates are the first-line pharmacologic treatment for postmenopausal osteoporosis and the most commonly prescribed medication for this condition.1 Bisphosphonates, classified as antiresorptive agents,...
Recent Resources
Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD: A Systematic Review
Objectives. To synthesize existing knowledge about the effectiveness and harms of pharmacologic and nonpharmacologic treatments for exacerbations of chronic obstructive pulmonary disease (ECOPD).
Data sources. Embase®, Epub Ahead of Print, In-Process...
Keywords/Tags:
Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial
BACKGROUND:
The potential role of new oral anticoagulants in antiphospholipid antibody syndrome (APS) remains uncertain.
OBJECTIVE:
To determine whether rivaroxaban is noninferior to dose-adjusted vitamin K antagonists (VKAs) for thrombotic APS.
DESIGN:
3-year...
Keywords/Tags:
Primary Prevention of Cardiovascular Disease
Atherosclerotic CVD remains the leading cause of death for people of most racial/ethnic groups. In 2010, the AHA suggested metrics of ideal cardiovascular health in 7 domains (blood pressure, physical activity, cholesterol, diet, weight, smoking, and blood glucose). There have since been...
Keywords/Tags:
Subconcussive Football Hits May Leave a Telltale Signature of Brain Damage
College football players in the United States endure over 1000 head hits every season. Although many don’t produce symptoms such as dizziness or blurred vision that often accompany frank concussion, these “clinically silent” hits are associated with the same type of brain damage as concussion,...
Keywords/Tags:
Unprocessed Red Meat and Processed Meat Consumption: Dietary Guideline Recommendations From the Nutritional Recommendations (NutriRECS) Consortium
DESCRIPTION:
Dietary guideline recommendations require consideration of the certainty in the evidence, the magnitude of potential benefits and harms, and explicit consideration of people's values and preferences. A set of recommendations on red meat and processed meat consumption was...
Keywords/Tags:
Association between vitamin D supplementation and mortality: systematic review and meta-analysis
Abstract
OBJECTIVE:
To investigate whether vitamin D supplementation is associated with lower mortality in adults.
DESIGN:
Systematic review and meta-analysis of randomised controlled trials.
DATA SOURCES:
Medline, Embase, and the Cochrane Central...
Keywords/Tags:
Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2019-20 Influenza Season
Abstract
This report updates the 2018-19 recommendations of the Advisory Committee on Immunization Practices (ACIP) regarding the use of seasonal influenza vaccines in the United States (MMWR Recomm Rep 2018;67[No. RR-3]). Routine annual influenza vaccination is recommended for all...
Keywords/Tags:
Characteristics of Case Management in Primary Care Associated With Positive Outcomes for Frequent Users of Health Care: A Systematic Review
PURPOSE:
Case management (CM) interventions are effective for frequent users of health care services, but little is known about which intervention characteristics lead to positive outcomes. We sought to identify characteristics of CM that yield positive outcomes among frequent users with...
Keywords/Tags:
Clinical Approach to Lactose Intolerance
Lactose intolerance refers to the clinical syndrome in which symptoms of bloating, flatulence, abdominal discomfort, and diarrhea arise following the consumption of lactose-containing foods. Lactose malabsorption results from congenital lactase deficiency, secondary lactose intolerance, and,...
Keywords/Tags: