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Treatments for Acute Pain: A Systematic Review

Author/s: Agency for Healthcare Research and Quality

Not available
Keywords/Tags:
pain management

Clinical diagnosis of benign paroxysmal positional vertigo and vestibular neuritis

Author/s: Johns, Peter, Quinn, James

Not available
Keywords/Tags:
benign paroxysmal positional vertigo vestibular neuritis

Obesity in adults: a clinical practice guideline

Author/s: Wharton, Sean, Lau, David, Vallis, Michael, Sharma, Arya, Biertho, Laurent, Campbell-Scherer, Denise, Adamo, Kristi

Not available
Keywords/Tags:
obesity outcomes delivery of health care

Bupropion and Naltrexone in Methamphetamine Use Disorder

Author/s: Madhukar H., Walker, Robrina, Ling, Walter, Cruz, Adriane, Sharma, Guarav, Carmody, Thomas, Ghitza, Udi, Wahle, Aimee, Kim, Mora, Shores-Wilson, Kathy, Sparenborg, Steven, Coffin, Phillip

BACKGROUND

The use of naltrexone plus bupropion to treat methamphetamine use disorder has not been well studied.

METHODS

We conducted this multisite, double-blind, two-stage, placebo-controlled trial with the use of a sequential parallel comparison design to evaluate the...

Keywords/Tags:
methamphetamine addiction treatment

APOE ɛ4 Allele Testing and Risk of Alzheimer Disease

Author/s: Choudhury, Parichita, Boeve, Bradley F., Ramanan, Vijay K

A 64-year-old man presented with concern about an abnormal genetic test result for apolipoprotein E (APOE) obtained through his primary care physician. He reported forgetfulness and word-finding difficulties for 3 years but performed all activities of daily living independently and was...

Keywords/Tags:
dementia Alzheimer Disease Genetic testing

Overcoming Barriers to the Diagnosis and Treatment of Insomnia

Author/s: Roth, Thomas

Apply evidence-based diagnostic guidelines for patients who have clinical features consistent with insomnia. Use evidence-based guidelines to develop comprehensive treatment plans that include cognitive-behavioral therapy, pharmacologic treatment, and combination therapies to achieve optimal...

Keywords/Tags:
Insomnia cognitive behavioral therapy Insomnia medications

Maintaining Safety with SARS-CoV-2 Vaccines

Author/s: Castells, Mariana C., Phillips, Elizabeth J.

To date, the development of mRNA vaccines for the prevention of infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a success story, with no serious concerns identified in the ongoing phase 3 clinical trials....

Keywords/Tags:
SARS-CoV-2 SARS coronavirus COVID-19 COVID-19 vaccine vaccines mRNA vaccines Pfizer–BioNTech mRNA vaccine Pfizer

Polypharmacy Management in Older Patients

Author/s: Hoel, Robert W., Giddings-Connolly, Ryan M., Takahashi, Paul Y.

Medications to treat disease and extend life in our patients often amass in quantities, resulting in what has been termed "polypharmacy." This imprecise label usually describes the accumulation of 5, and often more, medications. Polypharmacy in advancing age frequently results in drug therapy...

Keywords/Tags:
RISEOK opioids elderly polypharmacy elderly patients older adults Elderly care

Association of Therapies With Reduced Pain and Improved Quality of Life in Patients With Fibromyalgia: A Systematic Review and Meta-analysis

Author/s: Mascarenhas, Rodrigo O., Souza, Mateus B., Oliveira, Murilo X., Lacerda, Ana C., Mendonca, Vanessa A., Henschke, Nicholas, Oliveira, Vinicius C.

Importance: Fibromyalgia is a chronic condition that results in a significant burden to individuals and society.

Objective: To investigate the effectiveness of therapies for reducing pain and improving quality of life (QOL) in people with fibromyalgia....

Keywords/Tags:
Fibromyalgia quality of life cognitive behavioral therapy pain management

REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19

Author/s: Weinreich, David M., Sivapalasingam, Sumathi, Norton, THomas,, Ali, Shazia, Gao, Haitao, Bhore, Rafia, Musser, Bret J., Soo, Yuhwen, Rofail, Diana, Im, Joseph, Perry, Christina, Pan, Cynthia, Hosain, Romana, Mahmood, Adnan, Davis, John D., Turner, Kenneth C., Hooper, Andrea T., Hamilton, Jennifer D., Baum, Alina, Kyratsous, Christos A., Kim, Yunji, Cook, Amanda, Kampman, Wendy, Kohli, Anita, Sachdeva. Yessica, Graber, Ximena, Kowal, Bari, DiCioccio, Thomas, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary, Yancopoulos, George D.

Background: Recent data suggest that complications and death from coronavirus disease 2019 (Covid-19) may be related to high viral loads.

Methods: In this ongoing, double-blind, phase 1-3 trial involving nonhospitalized patients with Covid-19, we...

Keywords/Tags:
COVID-19 COVID-19 vaccine SARS coronavirus SARS-CoV-2 Antibodies coronavirus

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