Author/s: Gibson, W., Molnar, F., Frank, C.
Clinical question
How should I assess my older patient who has urinary incontinence (UI)?
Bottom line
Urinary incontinence, the involuntary loss of any urine, is a common problem among people older than 65 or those living with frailty but should not be considered part of “...
Author/s: Haseeb, M., Chhatwal, J., Xiao, J., Jirapinyo, P., Thompson, C.C.
Importance: Obesity is a disease with a large socioeconomic burden. Endoscopic sleeve gastroplasty (ESG) is a minimally invasive endoscopic bariatric procedure with wide global adoption. More recently, new weight-loss medications, such as glucagon-like peptide-1 receptor agonists (eg,...
Author/s: Chesire, W.P., Dudenkov, D.V., Munipalli, B.
A 43-year-old woman presented with a 1-year history of recurring symptoms of sudden onset of fatigue, palpitations, dyspnea, chest pain, lightheadedness, and nausea that were associated with standing and resolved with sitting. These symptoms began 1 month after mild COVID-19 infection. At...
Author/s: Chesire, W.P., Dudenkov, D.V., Munipalli, B.
A 43-year-old woman presented with a 1-year history of recurring symptoms of sudden onset of fatigue, palpitations, dyspnea, chest pain, lightheadedness, and nausea that were associated with standing and resolved with sitting. These symptoms began 1 month after mild COVID-19 infection. At...
Author/s: Marsh, E.E., Wegienka, G., Williams, D.R.
Uterine fibroids are sex–steroid responsive benign tumors primarily composed of smooth muscle cells and extracellular matrix that develop in the wall of the uterus.1 They are one of the most common neoplasms in reproductive-aged women. Lifetime prevalence estimates in premenopausal women range...
Author/s: Siegel, C.H., Sammaritano, L.R.
Importance
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by inflammation and immune-mediated injury to multiple organ systems, including the mucocutaneous, musculoskeletal, hematologic, and kidney systems. Approximately 3.4 million people worldwide have...
Author/s: Gerolymos, C, Barazer, R, Yon, D.K., Loundou, A, Boyer, L, Fond, G
Importance: Antipsychotic-induced akathisia (AIA) occurs in 14% to 35% of patients treated with antipsychotics and is associated with increased suicide and decreased adherence in patients with schizophrenia. However, no comprehensive review and network meta-analysis has been conducted to compare...
Author/s: Lee, JK, Roy, A., Jensen, C.D., Chan, J.T., Zhao, W.K.
Importance
Postpolypectomy surveillance is a common colonoscopy indication in older adults; however, guidelines provide little direction on when to stop surveillance in this population.
Objective
To estimate surveillance colonoscopy yields in older adults.
Design,...
Author/s: Wood RA, Togias A, Sicherer SH, Shreffler WG, Kim EH, Jones SM
BACKGROUND
Food allergies are common and are associated with substantial morbidity; the only approved treatment is oral immunotherapy for peanut allergy.
METHODS
In this trial, we assessed whether omalizumab, a monoclonal anti-IgE antibody, would be effective and safe as...
Author/s: Peterson, BS, Trampush, J, Maglione, M, Bolshakova, M, Brown, M., Rozelle, M
Objective. The systematic review assessed evidence on the diagnosis, treatment, and monitoring of attention deficit hyperactivity disorder (ADHD) in children and adolescents to inform a planned update of the American Academy of Pediatrics (AAP) guidelines.
Data sources. We searched PubMed...