Although cobalamin (vitamin B12) deficiency was described over a century ago, it is still difficult toestablish the correct diagnosis and prescribe the right treatment. Symptoms related to vitamin B12 deficiency may be diverse and vary from neurologic to psychiatric. A number of individuals with...
Library & Search Results
The Many Faces of Cobalamin (Vitamin B12) Deficiency
Although cobalamin (vitamin B12) deficiency was described over a century ago, it is still difficult toestablish the correct diagnosis and prescribe the right treatment. Symptoms related to vitamin B12 deficiency may be diverse and vary from neurologic to psychiatric. A number of individuals with...
New Approaches to Management of Depression
Interview with Andrew A. Nierenberg, MD, author of Evolving Issues in the Treatment of Depression
Grommets (ventilation tubes) for recurrent acute otitis media in children
BACKGROUND:
Acute otitis media (AOM) is one of the most common childhood illnesses. While many children experience sporadic AOM episodes, an important group suffer from recurrent AOM (rAOM), defined as three or more episodes in six months, or four or more in one year. In this subset of ...
Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review
BACKGROUND:
Optimal long-term osteoporosis drug treatment (ODT) is uncertain.
PURPOSE:
To summarize the effects of long-term ODT and ODT discontinuation and holidays.
DATA SOURCES:
Electronic bibliographic databases (January 1995 to October 2018) and systematic...
Management of Hepatitis C in 2019.
In the United States, hepatitis C virus (HCV) infection affects more than 2 million adults and is the leading cause of liver-related mortality. Therapies that eradicate HCV may prevent progression to cirrhosis, liver decompensation, hepatocellular carcinoma, need for liver transplant, and death...
Hip Fractures in Older Adults in 2019
The incidence of osteoporotic fracture increases exponentially throughout life, as does the risk of the devastating consequences of these fractures, including functional decline, institutionalization, mortality, and destitution....
Abnormal Uterine Bleeding in Reproductive-Age Women
Abnormal uterine bleeding (AUB) in reproductive-age women (defined as abnormal in duration, quantity, or timing) is experienced by approximtely one-third of all women throughout their lifetime, impairs quality of life, and can be effectively managed medically in most cases....
Chronic Constipation
Constipation is a common symptom that may be primary (idiopathic or functional) or associated with a number of disorders or medications. Although most constipation is self-managed by patients, 22% seek health care, mostly to primary care physicians (>50%) and gastroenterologists (14%),...
Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation
BACKGROUND:
Nicotine replacement therapy (NRT) aims to replace nicotine from cigarettes to ease the transition from cigarette smoking to abstinence. It works by reducing the intensity of craving and withdrawal symptoms. Although there is clear evidence that NRT used after smoking ...