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Unilateral Strength Training Leads to Muscle-Specific Sparing Effects During Opposite Homologous Limb Immobilization

Author/s: Andrushko, Justin W., Lanovaz, Joel L., Björkman, Kelsey M., Kontulainen, Saija A., Farthing, Jonathan P.

Cross education (CE) occurs after unilateral training whereby performance of the untrained contralateral limb is enhanced. A few studies have shown that CE can preserve or “spare” strength and size of an opposite immobilized limb, but the specificity (i.e., trained homologous muscle and...

Keywords/Tags:
strength training resistance training

Effect of Early Surgery vs Physical Therapy on Knee Function Among Patients With Nonobstructive Meniscal Tears The ESCAPE Randomized Clinical Trial

Author/s: van de Graaf, Victor A., Noorduyn, Julia C., Willigenburg, Nienke W., Butter, Ise K., de Gast, Arthur, Mol, Ben W., Saris, Daniel B. F., Twisk, Jos W. R., Poolman, Rudolf W.

IMPORTANCE

Despite recent studies suggesting arthroscopic partial meniscectomy (APM) is not more effective than physical therapy (PT), the procedure is still frequently performed in patients with meniscal tears.

OBJECTIVE

To assess whether PT is noninferior to APM for...

Keywords/Tags:
meniscal tear physical therapy arthoscopic surgery

Effects of an Angiotensin-Converting–Enzyme Inhibitor, Ramipril, on Cardiovascular Events in High-Risk Patients

Author/s: Yusuf, Salim

BACKGROUND:

Angiotensin-converting-enzyme inhibitors improve the outcome among patients with left ventricular dysfunction, whether or not they have heart failure. We assessed the role of an angiotensin-converting-enzyme inhibitor, ramipril, in patients who were at high risk for...

Keywords/Tags:
rampril cardiovascular events

Screening for Cervical Cancer: US Preventive Services Task Force Recommendation Statement.

Author/s: US Preventive Services Task Force

IMPORTANCE:

The number of deaths from cervical cancer in the United States has decreased substantially since the implementation of widespread cervical cancer screening and has declined from 2.8 to 2.3 deaths per 100 000 women from 2000 to 2015.

OBJECTIVE:

To update the US...

Keywords/Tags:
cervical cancer screening

The World Health Organization Adult Attention-Deficit/Hyperactivity Disorder Self-Report Screening Scale for DSM-5

Author/s: Ustun, Berk, Adler, Lenard A., Rudin, Cynthia, Faraone, Stephen V., Spencer, Thomas J., Berglund, Patricia, Gruber, Michael J., Kessler, Ronald C.

IMPORTANCE:

Recognition that adult attention-deficit/hyperactivity disorder (ADHD) is common, seriously impairing, and usually undiagnosed has led to the development of adult ADHD screening scales for use in community, workplace, and primary care settings. However, these scales are all...

Keywords/Tags:
ADHD DSM Self report

Antibiotics After Incision and Drainage for Uncomplicated Skin Abscesses: A Clinical Practice Guide

Author/s: Vermandere, Mieke, Aertgeerts, Bert, Agoritsas, Thomas, Liu, Catherine, Burgers, Jako, Merglen, Arnaud, Okwen, Patrick Mbah, Lytvyn, Lyubov, Chua, Shunjie, Vandvik, Per O., Guyatt, Gordon H., Beltran-Arroyave, Claudia, Lavergne, Valéry, Speeckaert, Reinhart, Steen, Finn E., Arteaga, Victoria, Sender, Rachelle, McLeod, Shelley, Sun, Xin, Wang, Wen, Siemieniuk, Reed A.C.

What you need to know

  • For uncomplicated skin abscesses, we suggest using trimethoprim-sulfamethoxazole (TMP-SMX) or clindamycin in addition to incision and drainage rather than incision and drainage alone, and emphasise the need for shared decision making

  • TMP-...

Keywords/Tags:
abscess drainage antibiotics TMP-SMX clindamycin

Efficacy of Vaginal Estradiol or Vaginal Moisturizer vs Placebo for Treating Postmenopausal Vulvovaginal Symptoms: A Randomized Clinical Trial

Author/s: Mitchell, Caroline M., Reed, Susan D., Diem, Susan, Larson, Joseph C., Newton, Katherine M., Ensrud, Kristine E., LaCroix, Andrea Z., Caan, Bette, Guthrie, Katherine A.

IMPORTANCE:

Nearly half of postmenopausal women report bothersome vulvovaginal symptoms, but few data support the efficacy of 2 commonly recommended treatments.

OBJECTIVE:

To compare the efficacy of a low-dose vaginal estradiol tablet and a vaginal moisturizer, each vs...

Keywords/Tags:
postmenopause estradiol moisturizing gel

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