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Discriminating Multisystem Inflammatory Syndrome in Children Requiring Treatment from Common Febrile Conditions in Outpatient Settings

Author/s: Carlin, Rebecca F., Fischer, Avital M., Pitlowsky, Zachary, Abel, Dori, Sewell, Taylor B., Landau, Erika G., Caddle, Steve, Robbins-Milne, Laura, Boneparth, Alexis, Milner, Josh D., Cheung, Eva W., Zachariah, Philp, Stockwell, Mellissa S., Anderson, Brett R., Gorelik, Mark

Objectives: To examine whether patients with multisystem inflammatory syndrome in children (MIS-C) demonstrated well-defined clinical features distinct from other febrile outpatients, given the difficulties of seeing acute care visits during the severe acute respiratory syndrome...

Keywords/Tags:
kawasaki disease SARS-CoV-2 multisystem inflammatory syndrome in children myocarditis COVID-19 coronavirus

Development and Assessment of a Pictographic Pediatric Constipation Action Plan

Author/s: Reeves, Patrick T., Kolasinski, Nathan T., Shonna YIn, H., Alqurashi, Waleed, Echelmeyer, Sofia, Chumpitazi, Bruno P., Rogers, Philip L., Burklow, Carolyn S., Nylund, Cade M.

Objective: To assess the Uniformed Services Constipation Action Plan (USCAP) as an evidence-based, personalized, clinical action tool with pictograms to aid clinicians and families in the management of functional constipation.

Study design: The USCAP...

Keywords/Tags:
Discharge Planning Functional Gastroenterology patient education Pictogram Validation

Clinical diagnosis of benign paroxysmal positional vertigo and vestibular neuritis

Author/s: Johns, Peter, Quinn, James

Not available
Keywords/Tags:
benign paroxysmal positional vertigo vestibular neuritis

Bupropion and Naltrexone in Methamphetamine Use Disorder

Author/s: Madhukar H., Walker, Robrina, Ling, Walter, Cruz, Adriane, Sharma, Guarav, Carmody, Thomas, Ghitza, Udi, Wahle, Aimee, Kim, Mora, Shores-Wilson, Kathy, Sparenborg, Steven, Coffin, Phillip

BACKGROUND

The use of naltrexone plus bupropion to treat methamphetamine use disorder has not been well studied.

METHODS

We conducted this multisite, double-blind, two-stage, placebo-controlled trial with the use of a sequential parallel comparison design to evaluate the...

Keywords/Tags:
methamphetamine addiction treatment

Weekly and Monthly Subcutaneous Buprenorphine Depot Formulations vs Daily Sublingual Buprenorphine With Naloxone for Treatment of Opioid Use Disorder: A Randomized Clinical Trial

Author/s: Lofwall, Michelle R., Walsh, Sharon L., Nunes, Edward V., Bailey, Genie L., Sigmon, Stacey C., Kampman, Kyle M., Frost, Michael, Tiberg, Fredrik, Linden, Marareta, Sheldon, Behshad, Oosman, Sonia, Peterson, Stefan, Chen, Michael, Kim, Sonnie

Importance: Buprenorphine treatment for opioid use disorder may be improved by sustained-release formulations.

Objective: To determine whether treatment involving novel weekly and monthly subcutaneous (SC) buprenorphine depot formulations is noninferior...

Keywords/Tags:
opioids Opioid Use Disorder Buprenorphine Buprenorphine-naloxone

Stepped Exercise Program for Patients With Knee Osteoarthritis: A Randomized Controlled Trial

Author/s: Allen, Kelli D., Bongiorni, Dennis, Caves, Kevin, Coffman, Cynthia J., Floegel, Theresa A., Greysen, Heather M., Hall, Katherine S., Heiderscheit, Bryan, Hoenig, Helen M., Huffman, Kim M., Morey, Miriam D., Ramasunder, Shalini, Severson, Herbert, Smith, Battista, Van Houtven, Courtney, Woolson, Sandra

Background: Physical therapy (PT) and other exercise-based interventions are core components of care for knee osteoarthritis (OA), but both are underutilized, and some patients have limited access to PT services. This clinical trial is examining a STepped Exercise Program for...

Keywords/Tags:
osteoarthritis Knee osteoarthritis Knee Joint veterans exercise therapy

Glucosamine/Chondroitin and Mortality in a US NHANES Cohort

Author/s: King, Dana E., Xiang, Jun

Background: Limited previous studies in the United Kingdom or a single US state have demonstrated an association between intake of glucosamine/chondroitin and mortality. This study sought to investigate the association between regular consumption of glucosamine/chondroitin and...

Keywords/Tags:
Chondroitin Cardiovascular Diseases Glucosamine Cohort Studies Nutrition Surveys osteoarthritis Proportional Hazards Models

Dynamics and Correlation Among Viral Positivity, Seroconversion, and Disease Severity in COVID-19

Author/s: Fu, Yu, Li, Yongsheng, Guo, Ensong, He, Liang, Liu, Jia, Yang, Bin, Li, Fuxia, Wang, Zizhuo, Li, Yuan, Xiao, Rourou, Liu, Chen, Huang, Yuhan, Wu, Xue, Lu, Funian, You, Lixin, Qin, Tianyu, Wang, Chaolong, Li, Kezhen, Wu, Peng, Ma, Ding, Sun, Chaoyang, Chen, Gang

Background: The understanding of viral positivity and seroconversion during the course of coronavirus disease 2019 (COVID-19) is limited.

Objective: To describe patterns of viral polymerase chain reaction (PCR) positivity and evaluate their correlations...

Keywords/Tags:
COVID-19 coronavirus SARS coronavirus Polymerase chain reaction PCR

Effect of Vitamin D3 Supplements on Development of Advanced Cancer: A Secondary Analysis of the VITAL Randomized Clinical Trial

Author/s: Chandler, P.D., Chen, W.Y., Ojala, O.N.

Importance  Epidemiologic and trial data suggest that vitamin D supplementation may reduce metastatic cancer and cancer mortality, reflecting shared biological pathways.

Objective  To follow up on the possible reduction in cancer death in the Vitamin D...

The effect of curcumin ointment on knee pain in older adults with osteoarthritis: a randomized placebo trial

Author/s: Jamali, N., Adib-Hajbaghery, M., Soleimani, A.

Abstract

Background: Some studies have shown the effect of oral administration of curcumin on knee pain. However, limited studies are available on the effect of topical curcumin. This study aimed to investigate the effect of curcumin ointment on knee pain in older adults...

Keywords/Tags:
curcumin Knee pain elderly Ointment osteoarthritis

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