Abstract
Objective To investigate the effectiveness of using convalescent plasma to treat moderate coronavirus disease 2019 (covid-19) in adults in India.
Design Open label, parallel arm, phase II, multicentre, randomised controlled trial.
...
Library & Search Results
Life Expectancy after Bariatric Surgery in the Swedish Obese Subjects Study
BACKGROUND
Obesity shortens life expectancy. Bariatric surgery is known to reduce the long-term relative risk of death, but its effect on life expectancy is unclear.
METHODS
We used the Gompertz proportional hazards regression model to compare mortality and life expectancy...
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Risk for Serious Infection With Low-Dose Glucocorticoids in Patients With Rheumatoid Arthritis
Abstract
Background: Low-dose glucocorticoids are frequently used for the management of rheumatoid arthritis (RA) and other chronic conditions, but the safety of long-term use remains uncertain.
Objective: To quantify the risk for hospitalized...
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Patient-Reported Needs Following a Referral for Colorectal Cancer Screening
Abstract
Introduction: Patient-physician communication about colorectal cancer screening can affect screening use, but discussions often lack information that patients need for informed decision making and seldom address personal preferences or barriers. To address this...
Kinetics of viral clearance and antibody production across age groups in SARS-CoV-2 infected children
Abstract
Objectives: To improve understanding of transition from viral infection to viral clearance, and antibody response in pediatric patients with SARS-CoV-2 infection.
Study design: This retrospective analysis of children tested for SARS-CoV-2...
A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis
BACKGROUND
Antibiotic therapy has been proposed as an alternative to surgery for the treatment of appendicitis.
METHODS
We conducted a pragmatic, nonblinded, noninferiority, randomized trial comparing antibiotic therapy (10-day course) with appendectomy in patients with...
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Effects of weight loss during a very low carbohydrate diet on specific adipose tissue depots and insulin sensitivity in older adults with obesity: a randomized clinical trial
Background: Insulin resistance and accumulation of visceral adipose tissue (VAT) and intermuscular adipose tissue (IMAT) place aging adults with obesity at high risk of cardio-metabolic disease. A very low carbohydrate diet (VLCD) may be a means of promoting fat loss from the...
Human Papillomavirus Immunization in Rural Primary Care
Abstract
Introduction: Despite the safety and efficacy of the human papillomavirus vaccine, thousands are impacted by human papillomavirus and its related cancers. Rural regions have disproportionately low rates of human papillomavirus vaccination. Primary care clinics...
COVID-19–Associated Multisystem Inflammatory Syndrome in Children — United States, March–July 2020
Summary
What is already known about this topic?
Multisystem inflammatory syndrome in children (MIS-C) is a rare but severe condition that has been reported approximately 2–4 weeks after the onset of COVID-19 in children and adolescents.
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Association of Menopausal Hormone Therapy With Breast Cancer Incidence and Mortality During Long-term Follow-up of the Women's Health Initiative Randomized Clinical Trials
Abstract
Importance: The influence of menopausal hormone therapy on breast cancer remains unsettled with discordant findings from observational studies and randomized clinical trials.
Objective: To assess the association of prior randomized use of...