Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism, ovulatory dysfunction, and
polycystic ovaries. Its etiology remains unknown, and treatment is largely symptom based and empirical. PCOS has the
potential to cause substantial metabolic sequelae,...
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Polycystic Ovary Syndrome
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Medicare’s Direct Provider Contracting: To Primary Care And Beyond
Direct provider contracting (DPC) is coming to Medicare.
Under a new announcement about reforming health care payment and delivery, the Centers for Medicare and Medicaid Services (CMS) has announced forthcoming DPC models as part of the effort to “...
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Medication Overload: America’s Other Drug Problem. How the drive to prescribe is harming older adults.
In the last year, older adults in the U.S. sought medical care nearly 5 million times due to serious side effects from one or more medications. More than a quarter million of these visits resulted in hospitalizations, at a cost of $3.8 billion (see Appendix A in the full report). These numbers...
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Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study
IMPORTANCE:
Anticholinergic medicines have short-term cognitive adverse effects, but it is uncertain whether long-term use of these drugs is associated with an increased risk of dementia.
OBJECTIVE:
To assess associations between anticholinergic drug treatments and risk of ...
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Guidelines for the Primary and Gender-Affirming Care of Transgender and Gender Nonbinary People
Introduction to the guidelines The Center of Excellence for Transgender Health (CoE) at the University of California – San Francisco is proud to present these Guidelines for the Primary and Gender-Affirming Care of Transgender and Gender Nonbinary People. Transgender people have a gender...
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Deficient Functioning of Frontostriatal Circuits During the Resolution of Cognitive Conflict in Cannabis-Using Youth
Abstract
OBJECTIVE:
Disturbances in self-regulatory control are involved in the initiation and maintenance of addiction, including cannabis use disorder. In adults, long-term cannabis use is associated with disturbances in frontostriatal circuits during tasks that require the...
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Associations between gabapentinoids and suicidal behaviour, unintentional overdoses, injuries, road traffic incidents, and violent crime: population based cohort study in Sweden
Abstract
OBJECTIVE:
To examine associations between gabapentinoids and adverse outcomes related to coordination disturbances (head or body injuries, or both and road traffic incidents or offences), mental health (suicidal behaviour, unintentional overdoses), and criminality.
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Ten tips for advancing a culture of improvement in primary care
Embracing practice-based quality improvement (QI) represents one way for clinicians to improve the care they provide to patients while also improving their own professional satisfaction. But engaging in care redesign is challenging for clinicians. In this article, we describe our experience over...
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Some benefits from donepezil in Alzheimer’s disease
CLINICAL QUESTION
How effective is exercise-based cardiac rehabilitation on mortality, morbidity, and health-related quality of life (QOL) in patients with coronary heart disease (CHD)?
BOTTOM LINE
Compared to usual care, in medium to longer-term follow-up (≥12 months)...
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Measles/Plan-for-Travel
Most measles cases in the U.S. result from international travel. Make sure you and your loved ones are protected against measles before international travel.
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