Author/s: Trivedi, Madhukar H., Walker, Robrina, Ling, Walter, Dela Cruz, Adriane, Sharma, Gaurav, Carmody, Thomas, Ghitza, Udi E., Wahle, Aimee, Kim, Mora, Shores-Wilson, Kathy, Sparenborg, Steven, Coffin, Philip, Schmitz, Joy, Wiest, Katharina, Bart, Gavin, Sonne, Susan C., Wakhlu, Sidarth, Rush, A.J., Nunes, Edward V., Shoptaw, Steven
BACKGROUND
The use of naltrexone plus bupropion to treat methamphetamine use disorder has not been well studied.
METHODS
We conducted this multisite, double-blind, two-stage, placebo-controlled trial with the use of a sequential parallel comparison design to evaluate the...
Author/s: Syr, Sancta St., Lindley, Barbee, Workowski, Kimberly A., Bachmann, Laura, Pham, Cau, Schlanger, Karen, Torrone, Elizabeth
Author/s: Agency for Healthcare Research and Quality
Author/s: Johns, Peter, Quinn, James
Author/s: Wharton, Sean, Lau, David, Vallis, Michael, Sharma, Arya, Biertho, Laurent, Campbell-Scherer, Denise, Adamo, Kristi
Author/s: Madhukar H., Walker, Robrina, Ling, Walter, Cruz, Adriane, Sharma, Guarav, Carmody, Thomas, Ghitza, Udi, Wahle, Aimee, Kim, Mora, Shores-Wilson, Kathy, Sparenborg, Steven, Coffin, Phillip
BACKGROUND
The use of naltrexone plus bupropion to treat methamphetamine use disorder has not been well studied.
METHODS
We conducted this multisite, double-blind, two-stage, placebo-controlled trial with the use of a sequential parallel comparison design to evaluate the...
Author/s: Choudhury, Parichita, Boeve, Bradley F., Ramanan, Vijay K
A 64-year-old man presented with concern about an abnormal genetic test result for apolipoprotein E (APOE) obtained through his primary care physician. He reported forgetfulness and word-finding difficulties for 3 years but performed all activities of daily living independently and was...
Author/s: Roth, Thomas
Apply evidence-based diagnostic guidelines for patients who have clinical features consistent with insomnia. Use evidence-based guidelines to develop comprehensive treatment plans that include cognitive-behavioral therapy, pharmacologic treatment, and combination therapies to achieve optimal...
Author/s: Castells, Mariana C., Phillips, Elizabeth J.
To date, the development of mRNA vaccines for the prevention of infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a success story, with no serious concerns identified in the ongoing phase 3 clinical trials....
Author/s: Hoel, Robert W., Giddings-Connolly, Ryan M., Takahashi, Paul Y.
Medications to treat disease and extend life in our patients often amass in quantities, resulting in what has been termed "polypharmacy." This imprecise label usually describes the accumulation of 5, and often more, medications. Polypharmacy in advancing age frequently results in drug therapy...