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Physical Activity: Home-based Exercise Interventions for Adults Aged 65 years and Older

The Community Preventive Services Task Force (CPSTF) recommends home-based exercise interventions to improve physical fitness (i.e., muscle strength, muscle power, muscle endurance, balance) among adults aged 65 years and older. The Physical Activity Guidelines for Americans, 2nd edition...

Keywords/Tags:
Retired Over 65 exercise Physical Fitness Fitness

Progression of Atrial Fibrillation after Cryoablation or Drug Therapy

Author/s: Andrade, J.G., Deyell, M. W., Macle, L., Wells, G. A., Bennett, M., Essebag, V., Champagne, J., Roux, J., Yung, D., Skanes, A., Khaykin, Y., Morillo, C., Jolly, U., Novak, P., Lockwood, E., Cadrin-Tourigny, J., Kochhäuser, S., Verma, A.

Background: Atrial fibrillation is a chronic, progressive disorder, and persistent forms of atrial fibrillation are associated with increased risks of thromboembolism and heart failure. Catheter ablation as initial therapy may modify the pathogenic mechanism of atrial fibrillation and alter...

Keywords/Tags:
quality of life Tachycardia Patient Acceptance of Health Care Catheters Confidence Intervals

Effect of fluvoxamine on outcomes of nonhospitalized patients with COVID-19: A systematic review and meta-analysis

Author/s: Lu, L., Chao, C., Chang, S., Lan, S., Lai, C.

Objectives: This meta-analysis investigated the use of fluvoxamine for the treatment of nonhospitalized patients with COVID-19.

Methods: PubMed, Web of Science, Ovid medline, Embase, Scopus, Cochrane Library databases, and ClinicalTrials.gov were searched for studies published before June...

Keywords/Tags:
Odds Ratio Artificial respiration control groups hospitalization bibliometrics

Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder

Author/s: O'Neil, M. E., Cheney, T. P., Hsu, F. C., Carlson, K. F., Hart, E. L., Holmes, R. S., Murphy, K. M., Graham, E., Cameron, D. C., Kahler, J., Lewis, M., Kaplan, J., McDonagh, M. S.

Objectives: Identify and abstract data from posttraumatic stress disorder (PTSD) treatment randomized controlled trials (RCTs) to update the PTSD Trials Standardized Data Repository (PTSD-Repository) with data on PTSD and mental health, including suicide-related outcomes and substance use.

...
Keywords/Tags:
PTSD Sample Size Health Policy referral and consultation MEDLINE

Health supervision for children with Down syndrome

Author/s: Bull, M. J., Committee on Genetics

These guidelines are designed to assist the pediatrician in caring for the child in whom a diagnosis of Down syndrome has been confirmed by chromosome analysis. Although a pediatrician's initial contact with the child is usually during infancy, occasionally the pregnant woman who has been given...

Keywords/Tags:
Academies and Institutes / standards* Age Factors Pediatrics / methods Pediatrics / standards* Genetic Counseling / standards

Hormone Therapy in Postmenopausal Persons: Primary Prevention of Chronic Conditions

Author/s: US Preventative Services task Force, Mangione, C. M., Barry, M. J., Nicholson, W. K., Cabana, M., Caughey, A. B., Chelmow, D., Coker, T. R., Davis, E. M., Donahue, K. E., Jaén, C. R., Kubik, M., Li, L., Ogedegbe, G., Pbert, L., Ruiz, J. M., Stevermer, J., Wong, J. B.

Importance: Menopause is defined as the cessation of a person's menstrual cycle. It is defined retrospectively, 12 months after the final menstrual period. Perimenopause, or the menopausal transition, is the few-year time period preceding a person's final menstrual period and is characterized by...

Keywords/Tags:
Retrospective Studies postmenopause Chronic Disease hormone therapy Recommendation Statement

Once-Weekly Semaglutide in Adolescents with Obesity

Author/s: Weghuber, D., Barrett, T.

BACKGROUND
A once-weekly, 2.4-mg dose of subcutaneous semaglutide, a glucagon-like peptide-1 receptor agonist, is used to treat obesity in adults, but assessment of the drug in adolescents has been lacking.

METHODS
In this double-blind, parallel-group, randomized, placebo-...

Keywords/Tags:
Cardiometabolic Risk Factors Confidence Intervals Glycated Hemoglobin A Waist Circumference Lipoproteins, HDL

Looking Back, Looking Forward: Current Medications and Innovative Potential Medications to Treat Alcohol Use Disorder

Author/s: Mason, B. J.

This article is part of a Festschrift commemorating the 50th anniversary of the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Established in 1970, first as part of the National Institute of Mental Health and later as an independent institute of the National Institutes of Health,...

Keywords/Tags:
alcohol alcoholism National Institute on Alcohol Abuse and Alcoholism (U.S.) National Institutes of Health (U.S.) naltrexone

A review on oral manifestations of COVID-19 disease

Author/s: Kumar, H., Nishat, R., Desai, A.

COVID-19, a multi-system-affecting disease presents with an extensive clinical spectrum, ranging from no symptoms at all to fatal lung involvement. Several orofacial manifestations have also been reported, among which dysgeusia is one of the earliest reported symptoms. Several other...

Keywords/Tags:
review oral manifestations COVID-19 disease comprehensive review

A “no-biopsy” approach to diagnosing celiac disease

Author/s: Mott, T., Gray, C., Storey, J.

PRACTICE CHANGER
CONSIDER A “NO-BIOPSY” APPROACH BY EVALUATING SERUM IMMUNOGLOBULIN (IG) A ANTI-TISSUE TRANSGLUTAMINASE (TTG-IGA) ANTIBODY TITERS IN ADULT PATIENTS WHO PRESENT WITH SYMPTOMS CONCERNING FOR CELIAC DISEASE (CD). AN INCREASE OF ≥ 10 TIMES THE UPPER LIMIT OF NORMAL (ULN) FOR...

Keywords/Tags:
celiac disease Gastroenterology diagnosis Predictive Value of Tests Alternative Approach

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