Author/s: Win Min Oo, Changhai Ding, Adam G. Culvenor, David J. Hunter
Importance: Approximately 5% of all primary care visits in adults are related to knee pain. Osteoarthritis (OA), patellofemoral pain, and meniscal tears are among the most common causes of knee pain.
Observations: Knee OA, affecting an estimated 654 million people worldwide, is the most...
Author/s: Evan Wood, Jessica Bright, Katrina Hsu, Nirupa Goel, Josey W.G. Ross, Averill Hanson, Rand Teed, Ginette Poulin, Bryany Denning, Kim Corace, Corrina Chase, Katelyn Halpape, Ronald Lim, Tim Kealey, Jürgen Rehm
Background: In Canada, low awareness of evidence-based interventions for the clinical management of alcohol use disorder exists among health care providers and people who could benefit from care. To address this gap, the Canadian Research Initiative in Substance Misuse convened a national...
Author/s: Josdalyne Anderson, Pooja Prabhu, M. Elise Graham
The lingual frenulum is a tissue fold created by tongue elevation. In ankyloglossia, oral examination may reveal a short, tight frenulum that inserts either toward the tongue tip or onto the mandibular alveolus (the tooth-bearing surface of the lower jaw). Clinicians should evaluate range of...
Author/s: Suzanne N. Morin, Sidney Feldman, Larry Funnell, Lora Giangregorio, Sandra Kim, Heather McDonald-Blumer, Nancy Santesso, Rowena Ridout, Wendy Ward
Fracture risk increases with advancing age, as a result of declining skeletal strength and increased risk of falling. In Canada, more than 2 million people live with osteoporosis.1 Every year in Canada, about 150 people per 100 000 suffer a hip fracture, which is considered among the most...
Author/s: Nicolas Dugré, Adrienne J. Lindblad, Danielle Perry, G. Michael Allan, Émélie Braschi, Jamie Falk, Liesbeth Froentjes, Scott R. Garrison, Jessica E.M. Kirkwood, Christina S. Korownyk
Objective: To assess the benefits and harms of lipid-lowering therapies used to prevent or manage cardiovascular disease including bile acid sequestrants (BAS), ezetimibe, fibrates, niacin, omega-3 supplements, proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors, and statins.
Author/s: Richard C. Waters, Meaghan Mugleston, Anina Terry, Carrie Reinhart, Megan Wilson
Background: Less than 20% of individuals with opioid use disorder (OUD) are receiving a medication treatment for OUD in the United States. Though nurses can assume critical roles in outpatient models of OUD care, there are no published reports of buprenorphine standing orders for nurses that...
Author/s: Shi, Yu, Wu, Wen
Chronic pain conditions impose significant burdens worldwide. Pharmacological treatments like opioids have limitations. Non-invasive non-pharmacological therapies (NINPT) encompass diverse interventions including physical, psychological, complementary and alternative approaches, and other...
Author/s: Chambers, Laura C., Hallowell, benjamin D., Zullo, Andrew R.
Question: Are higher doses of buprenorphine treatment for opioid use disorder associated with improved retention in treatment when use of fentanyl (vs heroin) is more prevalent?
Findings: In this cohort study of 6499 patients initiating buprenorphine treatment between 2016 and 2020,...
Author/s: Jeimy, Samira, Zhu, Rongbo
Tick-borne red meat allergy occurs from sensitization to a carbohydrate, galactose-α-1,3-galactose (α-gal)
The lone star tick (Amblyomma americanum) is commonly found in the southern United States, but its prevalence in Canada is increasing.1 The tick’s saliva contains a high level of α-...
Author/s: Carolyn D. Runowicz MD, Corinne R. Leach PhD, MS, MPH, N. Lynn Henry MD, PhD, Karen S. Henry MSN
The purpose of the American Cancer Society/American Society of Clinical Oncology Breast Cancer Survivorship Care Guideline is to provide recommendations to assist primary care and other clinicians in the care of female adult survivors of breast cancer. A systematic review of the literature was...