Author/s: Bernal, A. J., Gomes da Silva, M., Musungaie, D., Kovalchuk, E., Gonzalez, A., Delos Reyes, V., Martin-Quiros, A., Caraco, Y., Williams-Diaz, A., Brown, M., Du, J., Pedley, A., Assaid, C., Strizki, J., Grobler, J., Shamsuddin, H., Tipping, R., Wan, H., Paschke, A., Butterton, J., Johnson, M., De Anda, C., MOVe-OUT Study Group
Abstract
Background: New treatments are needed to reduce the risk of progression of coronavirus disease 2019 (Covid-19). Molnupiravir is an oral, small-molecule antiviral prodrug that is active against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Methods: We...
Author/s: Walter, K.
Pregnant and recently pregnant individuals who become infected with the COVID-19 virus
are at high risk of requiring extra medical care.
According to the Centers for Disease Control and Prevention (CDC),
between January 22, 2020, and November 29, 2021, 148 327
pregnant...
Author/s: US Preventative Services task Force
IMPORTANCE Dental caries is the most common chronic disease in children in the US.
According to the 2011-2016 National Health and Nutrition Examination Survey, approximately
23% of children aged 2 to 5 years had dental caries in their primary teeth. Prevalence is higher
in...
Author/s: Boelens Keun, J., Arnoldussen, I., Vriend, C., Van de Rest, O.
Although levodopa remains the most effective drug for symptomatic management of Parkinson's Disease (PD), treatment during advanced disease stages may raise unpredictable motor fluctuations and other complications. Counteracting these complications with other pharmacological therapies may prompt...
Author/s: Mevorach, D., Anis, E., Cedar, N., Bromberg, M., Haas, E. J., Nadir, E., Olsha-Castell, S., Arad, D., Hasin, T., Levi, N., Asleh, R., Amir, O., Meir, K., Cohen, D., Dichtiar, R., Novick, D., Hershkovitz, Y., Dagan, R., Leitersdorf, I., Ben-Ami, R., Miskin, I., Saliba, W., Muhsen, K., Levi, Y., Green, M. S., Beinan-Boker, L., Alroy-Preis, S.
Background: Approximately 5.1 million Israelis had been fully immunized against coronavirus disease 2019 (Covid-19) after receiving two doses of the BNT162b2 messenger RNA vaccine (Pfizer-BioNTech) by May 31, 2021. After early reports of myocarditis during adverse events monitoring, the Israeli...
Author/s: Kongsupon , N., Walters, G. I., Sadhra, S. S.
Background: Hypersensitivity pneumonitis (HP) is caused by a variety of antigens and low-molecular-weight chemicals, often through occupational exposure. Making a diagnosis of HP and identifying a cause are challenging. Cryptogenic cases are frequently reported, and missing or incomplete...
Author/s: Jiang, D. H., Roy, D. J., Gu, B. J., Hassett, L. C., McCoy, R. G.
The vast majority of patients (>99%) with severe acute respiratory syndrome coronavirus 2 survive immediate infection
but remain at risk for persistent and/or delayed multisystem. This review of published reports through May 31, 2021,
found that manifestations of postacute...
Author/s: M. J., Mangione, C. M., Cabana, M., Caughey, A. B., Davis, E. M., Donahue, K. E., Doubeni, C. A., Krist, A. H., Kubik, Li, L., Ogedegbe, G., Pbert, Silverstein, Simon, M. A., Stevermer, J., Tseng, C., Wong, J. B.
Importance: Chlamydia and gonorrhea are among the most common sexually transmitted infections in the US. Infection rates are highest among adolescents and young adults of both sexes. Chlamydial and gonococcal infections in women are usually asymptomatic and may lead to pelvic inflammatory...
Author/s: US Preventive Services Task Force, Davidson, K. W., Barry, M. J., Mangione, C. M., Cabana, M., Caughey, A. B., Davis, E. M., Donahue, K. E., Doubeni, C. A., Kubik, M., Li, L., Ogedegbe, G., Pbert, L., Silberstein, M., Stevermer, J., Tseng, C., Wong, J. B.
Importance: Gestational diabetes is diabetes that develops during pregnancy. Prevalence of gestational diabetes in the US has been estimated at 5.8% to 9.2%, based on traditional diagnostic criteria, although it may be higher if more inclusive criteria are used. Pregnant persons with gestational...
Author/s: Bifulco, L., Anderson, D. R., Blankson, M. L, Channamsetty, V., Blaz, J. W., Nguyen-Louie, T., Scholle, S. H.
Importance: Although pain is among the most common symptoms reported by patients, primary care practitioners (PCPs) face substantial challenges identifying and assessing pain.
Objective: To evaluate a 2-step process for chronic pain screening and follow-up in primary care.
Design,...