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Sleep as a vital sign

Author/s: Hirschtritt, M.E., Walker, M. P., Krystal, A.D.

Sleep is causally linked to the maintenance of every major physiological body system and disturbed sleep contributes to myriad diseases. The problem is, however, is that patients do not consistently, nor spontaneously, report sleep problems to their clinicians. Compounding the problem, there is...

Keywords/Tags:
sleep disrupted sleep sleep screenings

Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment

Author/s: Byrne, P., Demasi, M., Jones, M.

Importance The association between statin-induced reduction in low-density lipoprotein cholesterol (LDL-C) levels and the absolute risk reduction of individual, rather than composite, outcomes, such as all-cause mortality, myocardial infarction, or stroke, is unclear.

Objective To...

Keywords/Tags:
adult cholesterol stroke prevention

Postexposure Doxycycline to Prevent Bacterial Sexually Transmitted Infections

Author/s: Luetkemeyer, A. F., Donnell, D., Dombrowski, J. C., Cohen, S., Grabow, C., Brown, C. E., Malinski, C., Perkins, R., Nasser, M., Lopez, C., Vittinghoff, E., Buchbinder, S. P., Scott, H., Charlebois, E. D., Havlir, D. V., Soge, O. O., Celum, C., DoxyPEP Study Team

Background: Interventions to reduce sexually transmitted infections (STIs) among men who have sex with men (MSM) are needed.

Methods: We conducted an open-label, randomized study involving MSM and transgender women who were taking preexposure prophylaxis (PrEP) against human...

Keywords/Tags:
sexually transmitted diseases sexual and gender minorities primary prevention HIV prevention doxycycline

Lung cancer crash course

Author/s: Wilkinson, A. N.

Lung cancer has the highest mortality rate of any cancer in Canada, causing 25.5% of all cancer deaths, with a 5-year survival rate of only 19%. More than half of lung cancers are metastatic at diagnosis, with common sites of metastases in the brain, bone, liver, and adrenal glands. Lung cancer...

Keywords/Tags:
liver brain Survival Rate Small Cell Lung Carcinoma Canada

Approach to atrial fibrillation: Essentials for primary care

Author/s: Bell, A., Andrade, J. G., Macle, L., Connelly, K. A., LaBine, L., Singer, A. G.

Objective: To support family physicians in preventing atrial fibrillation (AF) in patients at risk and in identifying and managing those with established AF; and to summarize key recommendations for ideal screening and care of patients.

Sources of information: The 2020 Canadian...

Keywords/Tags:
atrial fibrillation anticoagulants stroke prevention primary health care Chronic Disease

2020 Focused Updates to the Asthma Management Guidelines: At-a-Glance Guide

This At-A-Glance Guide describes a treatment management approach based on recommendations from the 2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group. Step diagrams from...

Keywords/Tags:
management asthma stepwise approach guidelines updates

Patient-Reported Outcomes 12 Years after Localized Prostate Cancer Treatment

Author/s: Donovan, J. L., Hamdy, F. C., Lane, J. A., Young, G. J., Metcalfe, C., Walsh, E. I., Davis, M., Steuart-Feilding, T., Blazeby, J. M., Avery, K. N., Martin, R. M., Bollina, P., Doble, A., Doherty, A., Gillatt, D., Gnanapragasam, V., Hughes, O., Kockelbergh, R., Kynaston, H., Paul, A., Paez, E., Powell, P., Rosariom D. J., Rowe, E., Manson, M., Catto, J. W., Peters, T. J., Wade, J., Turner, E. L., Williams, N. J., Oxley, J., Staffurth, J., Bryant, R. J., Neal, D. E.

Long-term patient-reported outcomes are needed to inform treatment decisions for localized prostate cancer.

METHODS
Patient-reported outcomes of 1643 randomly assigned participants in the ProtecT (Prostate Testing for Cancer and Treatment) trial were evaluated to assess the...

Keywords/Tags:
Androgens Prostatectomy Patient Reported Outcome Measures prostate cancer surgery

What Parents Should Know About Sun and Sunburns in Children

Author/s: Wood, A. C., Albertini, L. W., Thompson, L. A.

When out with your children, it is important to protect them from sunrays on sunny and cloudy days. Every sunburn will increase a person’s risk of having skin cancer later in life. Practicing sun safety can prevent skin aging and cancer.

The sun makes 2 types of ultraviolet (UV) rays, UVA...

Keywords/Tags:
parents children skin cancer sunscreen preventing sunburn

Nocturnal hypoglycemia is underdiagnosed in older people with insulin-treated type 2 diabetes: The HYPOAGE observational study

Author/s: Boureau, A., Guyomarch, B., Gourdy, P., Allix, I., Annweiler, C., Cervantes, N., Chapelet, G., Delabriere, I., Guyonnet, S., Litke, R., Paccalin, M., Penfornis, A., Saulnier, P., Wargny, M., Hadjadj, S., de Decker, L., Cariou, B.

Background: There is a lack of real-life data regarding the frequency and predictive factors of hypoglycemia in older patients with type 2 diabetes (T2D). This study aimed to determine the frequency and predictors of hypoglycemia in older patients with insulin-treated T2D.

Methods: This...

Keywords/Tags:
basal insulin analogues continuous glucose monitoring glycemic control Hypoglycemics type 2 diabetes

Effect of an Intranasal Corticosteroid on Quality of Life and Local Microbiome in Young Children With Chronic Rhinosinusitis: A Randomized Clinical Trial

Author/s: Latek, M., Lacwik, P., Molinska, K., Blauz, A., Lach, J., Rychlik, B., Strapagiel, D., Majak, J., Czech, D., Seweryn, M., Kuna, P., Palczynski, C., Majak, P.

Importance: Intranasal corticosteroids (INCs) remain the first-line treatment of chronic rhinosinusitis (CRS) in both adults and children, despite the lack of evidence regarding their efficacy in the pediatric population. Similarly, their effect on the sinonasal microbiome has not been well...

Keywords/Tags:
quality of life Lymphocytes Child, Preschool Sodium Chloride / therapeutic use Chronic Disease

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