Background: Osteoporosis is an abnormal reduction in bone mass and bone deterioration, leading to increased fracture risk. Etidronate belongs to the bisphosphonate class of drugs which act to inhibit bone resorption by interfering with the activity of osteoclasts - bone cells that break down...
Library & Search Results
Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
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Interstitial Lung Disease: A Review
Importance: Interstitial lung disease (ILD) consists of a group of pulmonary disorders characterized by inflammation and/or fibrosis of the lung parenchyma associated with progressive dyspnea that frequently results in end-stage respiratory failure. In the US, ILD affects approximately 650 000...
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Measles
Canada has had measles elimination status since 1998 but remains vulnerable to outbreaks
Increased measles activity globally raises the risk of travel-related cases in Canada, which can spread rapidly in underimmunized communities.
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Arteriovenous Access for Hemodialysis: A Review
Importance: Hemodialysis requires reliable vascular access to the patient’s blood circulation, such as an arteriovenous access in the form of an autogenous arteriovenous fistula or nonautogenous arteriovenous graft. This Review addresses key issues associated with the construction and...
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Melanoma crash course
Cutaneous melanoma represents about 4% of skin cancers but is responsible for more than 75% of deaths from skin cancer. The incidence of cutaneous melanoma is reported as 25 per 100,000 people in North America and 60 per 100,000 people in Australia and New Zealand. Melanoma diagnoses are...
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Assessment of urinary incontinence in older adults, part 1
Clinical question
How should I assess my older patient who has urinary incontinence (UI)?
Bottom line
Urinary incontinence, the involuntary loss of any urine, is a common problem among people older than 65 or those living with frailty but should not be considered part of “...
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Examining for a Dislocated Hip in Infants
In many countries clinical examination is the primary screening tool to identify dislocated hips in newborns, with a positive screening examination typically triggering an ultrasound assessment of the hips. However, the condition is rare and the examination can be difficult to perform. We...
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Semaglutide vs Endoscopic Sleeve Gastroplasty for Weight Loss
Importance: Obesity is a disease with a large socioeconomic burden. Endoscopic sleeve gastroplasty (ESG) is a minimally invasive endoscopic bariatric procedure with wide global adoption. More recently, new weight-loss medications, such as glucagon-like peptide-1 receptor agonists (eg,...
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Tilt Table Testing
A 43-year-old woman presented with a 1-year history of recurring symptoms of sudden onset of fatigue, palpitations, dyspnea, chest pain, lightheadedness, and nausea that were associated with standing and resolved with sitting. These symptoms began 1 month after mild COVID-19 infection. At...
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Tilt Table Testing
A 43-year-old woman presented with a 1-year history of recurring symptoms of sudden onset of fatigue, palpitations, dyspnea, chest pain, lightheadedness, and nausea that were associated with standing and resolved with sitting. These symptoms began 1 month after mild COVID-19 infection. At...
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