Author/s: Leddy, John J., Haider, Mohammad N., Ellis, Michael J., Mannix, Rebekah, Darling, Scott R., Freitas, Michael S., Suffoletto, Heidi N., Leiter, Jeff, Cordingley, Dean M., Willer, Barry
IMPORTANCE:
Sport-related concussion (SRC) is a significant public health problem without an effective treatment.
OBJECTIVE:
To assess the effectiveness of subsymptom threshold aerobic exercise vs a placebo-like stretching program prescribed to adolescents in the acute phase...
Author/s: Sobieraj, D.M., Baker, W.L., Martinez, B.K., Hernandez, A.V., Coleman, C.I., Ross, J.S., Berg, K.M., Steffens, D.C.
Objective. To assess selected adverse events of antidepressants in the treatment of major depressive disorder (MDD) in adults 65 years old or older. Antidepressants included in this review, as determined by expert opinion, are selective serotonin reuptake inhibitors (SSRIs),...
Author/s: Willis, Deanna R., Zerr, Ann
Many family physicians chose the specialty of family medicine because of the value placed on the therapeutic relationship between the patient and the physician. When that relationship is significantly or repeatedly challenged, family physicians feel it deeply, and it’s not always clear how best...
Author/s: Hurley, Michael, Dickson, Kelly, Hallett, Rachel, Grant, Robert, Hauari, Hanan, Walsh, Nicola, Stansfield, Claire, Oliver, Sandy
BACKGROUND:
Chronic peripheral joint pain due to osteoarthritis (OA) is extremely prevalent and a major cause of physical dysfunction and psychosocial distress. Exercise is recommended to reduce joint pain and improve physical function, but the effect of exercise on psychosocial function...
Author/s: Chrisman, Sara P. D., Lowry, Sara, Herring, Stanley A., Kroshus, Emily, Hoopes, Teah R., Higgins, Shannon K., Rivara, Frederick P.
OBJECTIVE:
To collect prospective data on concussion incidence, risk factors, duration of symptoms, and return to school and sport in 5- to 14-year-old American football participants.
STUDY DESIGN:
We conducted a prospective cohort study over 2 years collecting data during...
Author/s: Dohrn, Ing-Mari, Kwak, Lydia, Oja, Pekka, Sjöström, Michael, Hagströmer, Maria
BACKGROUND:
Sedentary behavior is associated with health risks in adults. The potential benefits of reducing sedentary time may be dependent not only on decrease per se, but also on the type of activity it replaces. Few longitudinal studies have investigated the effects on mortality when...
Author/s: Madjd, Amenah, Taylor, Moira A., Delavari, Alireza,, Reza, Macdonald, Ian A., Farshchi, Hamid R.
OBJECTIVE:
This study aimed to evaluate the effect of different daily physical activity (PA) frequencies, while maintaining the same daily volume of PA, on weight loss, carbohydrate metabolism, and lipid metabolism in women with overweight or obesity throughout a 24-week intervention....
Author/s: Bright Futures, American Academy of Pediatrics
American Academy of Pediatrics Preventative Care Priodicity Guideline.
Author/s: Kahan, Scott, Manson, JoAnn E.
Author/s: Voelker, Rebecca
The Problem
Testing for BRCA1 and BRCA2 mutations identifies both benign and pathogenic genetic variants. But information about specific variants, particularly those of uncertain clinical significance (VUS), often isn’t systematically curated, expertly reviewed, or...