Background: Oklahoma's Advance Directive completion rate is less than 10%. We compared the implementation performance of 2 advance directive forms to determine which form could be more successfully disseminated.
Methods: The implementation of the Oklahoma Advance...
Statins (HMG-CoA reductase inhibitors) are one of the most widely prescribed medications in the world. However, their use in patients is often inappropriate because these medications have some unique properties not shared with other pharmaceuticals. This Commentary lists ten common...
Context
Proton pump inhibitors (PPIs) are among the most commonly used drugs worldwide, and have been linked to acute interstitial nephritis. Less is known about the relationship between PPI use and chronic kidney disease (CKD).
Objective
To quantify the association between...
Objectives
To estimate associations between long‐term use of proton pump inhibitors (PPIs) and pneumonia incidence in older adults in primary care.
Design
Longitudinal analyses of electronic medical records.
Setting
England
Participants
...
Background
Headaches resulting from proton pump inhibitor (PPI) use could cause discontinuation of PPI in as many as 40% of patients who experience such headaches. Previous studies focusing on acute headache risk from PPI use are rare and limited to clinical trials of a single PPI.
...BACKGROUND
Actinic keratosis is the most frequent premalignant skin disease in the white population. In current guidelines, no clear recommendations are made about which treatment is preferred.
METHODS
We investigated the effectiveness of four frequently used field-directed...
BACKGROUND:
Type 2 diabetes is a chronic disorder that requires lifelong treatment. We aimed to assess whether intensive weight management within routine primary care would achieve remission of type 2 diabetes.
METHODS:
We did this open-label, cluster-randomised trial (...
What is the problem and what is known about it so far?
Many parents choose not to vaccinate their children because of worry about autism, even though the 1998 study claiming to show that children who receive the measles, mumps, rubella (MMR) vaccine were at increased risk...
OBJECTIVE:
To analyze injuries that were directly associated with yoga practice and identify specific poses that should be avoided in patients with osteopenia or osteoporosis.
PATIENTS AND METHODS:
We retrospectively reviewed the medical records of patients with injuries...
OBJECTIVE:
To investigate the efficacy of yoga as antihypertensive lifestyle therapy and identify moderators that account for variability in the blood pressure (BP) response to yoga.
METHODS:
We systematically searched 6 electronic databases from inception through June 4,...
